猫茶 发表于 2022-1-15 11:32

心衰治疗还要补铁?是“雪中送炭”还是“锦上添花”?

<h2 style="font-weight: bold;white-space: normal;line-height: 1.6em;"><br/></h2><p><section data-support="96编辑器" data-style-id="31585" style="outline: 0px;font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;"><section style="margin-top: 10px;margin-bottom: 10px;outline: 0px;"><section style="margin-left: auto;outline: 0px;width: 2em;"><br data-filtered="filtered" style="outline: 0px;"/></section><section style="margin-top: -30px;margin-right: 10px;padding: 14px;outline: 0px;background-color: rgb(251, 235, 235);border-radius: 0px 20px 0px 0px;box-sizing: border-box;"><section style="outline: 0px;line-height: 1.75em;letter-spacing: 2px;font-size: 15px;transform: rotateZ(0deg);-webkit-transform: rotateZ(0deg);-moz-transform: rotateZ(0deg);-ms-transform: rotateZ(0deg);-o-transform: rotateZ(0deg);"><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;">&nbsp; &nbsp; &nbsp;&nbsp;心衰是所有心血管疾病的终末期阶段,70岁以上的老人中,每10个人就有一个人患有心衰,除了心衰病情的进展,危害呈渐进性发展。尽管对心衰发病机理研究的深入以及治疗方案的日新月异,但在心衰治疗的漫漫长路上却存在很多“拦路虎”。</span></p></section></section></section></section><section data-support="96编辑器" data-style-id="28090"><section style="margin-top: 10px;margin-bottom: 10px;text-align: center;"><section style="border-width: 1px;border-style: solid;border-color: rgb(255, 19, 13);box-sizing: border-box;"><section style="padding: 10px;color: rgb(255, 19, 13);box-sizing: border-box;"><p style="letter-spacing: 1px;"><br/></p></section></section></section></section><section data-support="96编辑器" data-style-id="31585" style="outline: 0px;font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;"><section style="margin-top: 10px;margin-bottom: 10px;outline: 0px;"><section style="margin-left: auto;outline: 0px;width: 2em;"><br data-filtered="filtered" style="outline: 0px;"/></section><section style="margin-top: -30px;margin-right: 10px;padding: 14px;outline: 0px;background-color: rgb(251, 235, 235);border-radius: 0px 20px 0px 0px;box-sizing: border-box;"><section style="outline: 0px;line-height: 1.75em;letter-spacing: 2px;font-size: 15px;transform: rotateZ(0deg);-webkit-transform: rotateZ(0deg);-moz-transform: rotateZ(0deg);-ms-transform: rotateZ(0deg);-o-transform: rotateZ(0deg);"><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;">&nbsp; &nbsp; &nbsp;&nbsp;临床研究发现,急性/慢性心衰患者中,其中铁缺乏占24%-75%,铁缺乏合并贫血占43%-78%,铁缺乏不合并贫血占15%-65%,从统计数据可以看出,贫血和缺铁在心衰患者中普遍存在,并且经常共同存在。同时研究还发现,铁缺乏伴或不伴贫血都与心衰的严重程度和不良预后密切相关,贫血会加重心衰症状,增加住院次数和时间,升高死亡率,与非贫血的患者相比,贫血患者心功能进展为III级或IV级的比例升高35%,死亡风险增加66%。</span></p></section></section></section></section><section data-support="96编辑器" data-style-id="26378"><section style="margin-top: 10px;margin-bottom: 10px;text-align: center;"><section style="display: inline-block;background-image: url(https://bbs.zhuzhou.com/plugin.php?id=wcn_editor:wx_img&url=https://mmbiz.qpic.cn/mmbiz_png/Ljib4So7yuWiaJIufeyibkYLmN0fiapgC2XLib61CibwrSmfhaBdZ6jf9VMDCv7JjQ1AicnRlibAdRjbr9DRZOLia8fOxZQ/640?wx_fmt=png);background-position: 50% 50%;background-repeat: no-repeat;background-size: 100%;background-attachment: scroll;border-width: 0px;border-radius: 3px;border-style: dashed;border-color: rgb(255, 129, 152);box-sizing: border-box;"><section><p style="padding: 20px 18px 20px 30px;white-space: normal;"><span data-form="2" data-num="1" style="color: #ffffff;font-size: 20px;">1</span><br/></p></section></section></section></section><section data-support="96编辑器" data-style-id="24026"><section style="margin-top: 10px;margin-bottom: 10px;"><p style="text-align: center;"><span data-form="0" data-num="1" style="color: #ff0000;font-size: 36px;"></span></p><section style="margin-top: -30px;margin-bottom: 10px;text-align: center;"><section style="vertical-align: middle;display: inline-block;width: 8px;height: 20px;background-color: #ff0000;"><br/></section><section style="margin-left: 10px;vertical-align: middle;display: inline-block;"><p><span style="letter-spacing: 0.5px;"><strong><span style="font-size: 16px;color: #ff4c41;">为什么心衰患者容易合并铁缺乏及贫血?</span></strong></span></p></section><section data-width="10%" style="height: 1px;vertical-align: middle;border-width: 1px;border-top-style: solid;border-color: rgb(60, 60, 60);display: inline-block;width: 10%;box-sizing: border-box;"><br/></section><section style="vertical-align: middle;display: inline-block;width: 10px;height: 10px;background-color: rgb(255, 0, 0);border-radius: 50%;box-sizing: border-box;"><br/></section></section></section></section></p><p style="letter-spacing: 1px;line-height: 2em;"><span style="font-size: 16px;"></span></p><p><section data-support="96编辑器" data-style-id="28090"><section style="margin-top: 10px;margin-bottom: 10px;text-align: center;"><section style="border-width: 1px;border-style: solid;border-color: rgb(255, 19, 13);box-sizing: border-box;"><section style="padding: 10px;color: rgb(255, 19, 13);box-sizing: border-box;"><p style="letter-spacing: 1px;"><br/></p></section></section></section></section><section data-support="96编辑器" data-style-id="31585" style="outline: 0px;font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;"><section style="margin-top: 10px;margin-bottom: 10px;outline: 0px;"><section style="margin-left: auto;outline: 0px;width: 2em;"><br data-filtered="filtered" style="outline: 0px;"/></section><section style="margin-top: -30px;margin-right: 10px;padding: 14px;outline: 0px;background-color: rgb(251, 235, 235);border-radius: 0px 20px 0px 0px;box-sizing: border-box;"><section style="outline: 0px;line-height: 1.75em;letter-spacing: 2px;font-size: 15px;transform: rotateZ(0deg);-webkit-transform: rotateZ(0deg);-moz-transform: rotateZ(0deg);-ms-transform: rotateZ(0deg);-o-transform: rotateZ(0deg);"><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;">&nbsp; &nbsp; &nbsp;&nbsp;心衰合并铁缺乏及贫血的发病机制比较复杂,可能与以下因素有关:</span></p><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;color: #ff4c41;">(1)促炎症反应</span><span style="font-size: 16px;">:心衰时多种炎性因子的大量释放,可抑制促红细胞生成素的分泌,同时抑制骨髓红细胞增生,并减少铁的吸收。</span></p><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;color: #ff4c41;">(2)造血原料缺乏</span><span style="font-size: 16px;">:心衰常常引起胃肠道淤血,消化道吸收铁的功能下降或药物影响铁的吸收,导致缺铁。</span></p><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;color: #ff4c41;">(3)促红细胞生成素合成相对不足</span><span style="font-size: 16px;">:心衰时易导致或并发肾功能损害,促红细胞生成素减少,而促红细胞生成素是红细胞合成的必需物质。</span></p><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;color: #ff4c41;">(4)药物影响</span><span style="font-size: 16px;">:心衰治疗药物血管紧张素转换酶抑制剂/血管紧张素受体拮抗剂类药物,不仅影响促红细胞生成素合成,还会抑制促红细胞生成素发挥促进红细胞生成的作用,使血红蛋白水平降低。</span></p></section></section></section></section><section data-support="96编辑器" data-style-id="26378"><section style="margin-top: 10px;margin-bottom: 10px;text-align: center;"><section style="display: inline-block;background-image: url(https://bbs.zhuzhou.com/plugin.php?id=wcn_editor:wx_img&url=https://mmbiz.qpic.cn/mmbiz_png/Ljib4So7yuWiaJIufeyibkYLmN0fiapgC2XLib61CibwrSmfhaBdZ6jf9VMDCv7JjQ1AicnRlibAdRjbr9DRZOLia8fOxZQ/640?wx_fmt=png);background-position: 50% 50%;background-repeat: no-repeat;background-size: 100%;background-attachment: scroll;border-width: 0px;border-radius: 3px;border-style: dashed;border-color: rgb(255, 129, 152);box-sizing: border-box;"><section><p style="padding: 20px 18px 20px 30px;white-space: normal;"><span data-form="2" data-num="1" style="color: #ffffff;font-size: 20px;">2</span><br/></p></section></section></section></section><section data-support="96编辑器" data-style-id="24026"><section style="margin-top: 10px;margin-bottom: 10px;"><p style="text-align: center;"><span data-form="0" data-num="1" style="color: #ff0000;font-size: 36px;"></span></p><section style="margin-top: -30px;margin-bottom: 10px;text-align: center;"><section style="vertical-align: middle;display: inline-block;width: 8px;height: 20px;background-color: #ff0000;"><br/></section><section style="margin-left: 10px;vertical-align: middle;display: inline-block;"><p><span style="letter-spacing: 0.5px;"><strong><span style="font-size: 16px;color: #ff4c41;">如何识别心衰患者合并铁缺乏及贫血?</span></strong></span></p></section><section data-width="10%" style="height: 1px;vertical-align: middle;border-width: 1px;border-top-style: solid;border-color: rgb(60, 60, 60);display: inline-block;width: 10%;box-sizing: border-box;"><br/></section><section style="vertical-align: middle;display: inline-block;width: 10px;height: 10px;background-color: rgb(255, 0, 0);border-radius: 50%;box-sizing: border-box;"><br/></section></section></section></section></p><p style="letter-spacing: 1px;line-height: 2em;"><span style="font-size: 16px;"></span></p><p><section data-support="96编辑器" data-style-id="28090"><section style="margin-top: 10px;margin-bottom: 10px;text-align: center;"><section style="border-width: 1px;border-style: solid;border-color: rgb(255, 19, 13);box-sizing: border-box;"><section style="padding: 10px;color: rgb(255, 19, 13);box-sizing: border-box;"><p style="letter-spacing: 1px;"><br/></p></section></section></section></section><section data-support="96编辑器" data-style-id="31585" style="outline: 0px;font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;"><section style="margin-top: 10px;margin-bottom: 10px;outline: 0px;"><section style="margin-left: auto;outline: 0px;width: 2em;"><br data-filtered="filtered" style="outline: 0px;"/></section><section style="margin-top: -30px;margin-right: 10px;padding: 14px;outline: 0px;background-color: rgb(251, 235, 235);border-radius: 0px 20px 0px 0px;box-sizing: border-box;"><section style="outline: 0px;line-height: 1.75em;letter-spacing: 2px;font-size: 15px;transform: rotateZ(0deg);-webkit-transform: rotateZ(0deg);-moz-transform: rotateZ(0deg);-ms-transform: rotateZ(0deg);-o-transform: rotateZ(0deg);"><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;">&nbsp; &nbsp; &nbsp;&nbsp;在《中国心力衰竭诊断和治疗指南2018》及《2021ESC心衰诊治指南》中明确指出所有的心衰患者均应筛查铁缺乏及贫血,应对所有心衰患者进行血常规、血清铁、铁蛋白及转铁蛋白饱和度检测。</span></p><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;">&nbsp; &nbsp; &nbsp;&nbsp;铁蛋白<100ug/L或铁蛋白100-299ug/L,但转铁蛋白饱和度<20%可诊断为铁缺乏,在此基础上血红蛋白<130g/L(男)/<120g/L(女)时,可诊断为心衰合并贫血。</span></p></section></section></section></section><section data-support="96编辑器" data-style-id="26378"><section style="margin-top: 10px;margin-bottom: 10px;text-align: center;"><section style="display: inline-block;background-image: url(https://bbs.zhuzhou.com/plugin.php?id=wcn_editor:wx_img&url=https://mmbiz.qpic.cn/mmbiz_png/Ljib4So7yuWiaJIufeyibkYLmN0fiapgC2XLib61CibwrSmfhaBdZ6jf9VMDCv7JjQ1AicnRlibAdRjbr9DRZOLia8fOxZQ/640?wx_fmt=png);background-position: 50% 50%;background-repeat: no-repeat;background-size: 100%;background-attachment: scroll;border-width: 0px;border-radius: 3px;border-style: dashed;border-color: rgb(255, 129, 152);box-sizing: border-box;"><section><p style="padding: 20px 18px 20px 30px;white-space: normal;"><span data-form="2" data-num="1" style="color: #ffffff;font-size: 20px;">3</span><br/></p></section></section></section></section><section data-support="96编辑器" data-style-id="24026"><section style="margin-top: 10px;margin-bottom: 10px;"><p style="text-align: center;"><span data-form="0" data-num="1" style="color: #ff0000;font-size: 36px;"></span></p><section style="margin-top: -30px;margin-bottom: 10px;text-align: center;"><section style="vertical-align: middle;display: inline-block;width: 8px;height: 20px;background-color: #ff0000;"><br/></section><section style="margin-left: 10px;vertical-align: middle;display: inline-block;"><p><span style="letter-spacing: 0.5px;"><strong><span style="font-size: 16px;color: #ff4c41;">心衰患者合并铁缺乏及贫血如何干预?</span></strong></span></p></section><section data-width="10%" style="height: 1px;vertical-align: middle;border-width: 1px;border-top-style: solid;border-color: rgb(60, 60, 60);display: inline-block;width: 10%;box-sizing: border-box;"><br/></section><section style="vertical-align: middle;display: inline-block;width: 10px;height: 10px;background-color: rgb(255, 0, 0);border-radius: 50%;box-sizing: border-box;"><br/></section></section></section></section></p><p style="letter-spacing: 1px;line-height: 2em;"><span style="font-size: 16px;"></span></p><p style="text-align: center;letter-spacing: 1px;line-height: 2em;"><span style="font-size: 16px;color: #ff4c41;">(1)补充铁剂治疗</span></p><p><section data-support="96编辑器" data-style-id="28090"><section style="margin-top: 10px;margin-bottom: 10px;text-align: center;"><section style="border-width: 1px;border-style: solid;border-color: rgb(255, 19, 13);box-sizing: border-box;"><section style="padding: 10px;color: rgb(255, 19, 13);box-sizing: border-box;"><p style="letter-spacing: 1px;"><br/></p></section></section></section></section><section data-support="96编辑器" data-style-id="31585" style="outline: 0px;font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;"><section style="margin-top: 10px;margin-bottom: 10px;outline: 0px;"><section style="margin-left: auto;outline: 0px;width: 2em;"><br data-filtered="filtered" style="outline: 0px;"/></section><section style="margin-top: -30px;margin-right: 10px;padding: 14px;outline: 0px;background-color: rgb(251, 235, 235);border-radius: 0px 20px 0px 0px;box-sizing: border-box;"><section style="outline: 0px;line-height: 1.75em;letter-spacing: 2px;font-size: 15px;transform: rotateZ(0deg);-webkit-transform: rotateZ(0deg);-moz-transform: rotateZ(0deg);-ms-transform: rotateZ(0deg);-o-transform: rotateZ(0deg);"><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;">&nbsp; &nbsp; &nbsp;&nbsp;一旦确诊铁缺乏,铁剂治疗应作为首选,铁剂分为口服和注射用铁剂两大类,根据病情严重程度和个人耐受情况,使用有所差异。口服铁剂起效慢,对胃肠道刺激比较大,部分患者不耐受;而静脉铁剂不良反应相对少,效果好,患者容易接受。2021年ESC心衰指南指出,有症状的心衰患者合并铁缺乏,建议进行静脉补铁治疗,以改善症状、提高运动耐量和生活质量。目前静脉铁剂主要有蔗糖铁、羧基麦芽糖铁和低分子右旋糖苷铁,其中羧基麦芽糖铁被认为具有良好的耐受性,不良反应最小。</span></p><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;">&nbsp; &nbsp; &nbsp;&nbsp;需要注意的是,无论以哪种形式补铁,都不可过量,注意定期复查血清铁等指标,以免引起铁中毒。在服用铁剂时,不宜喝咖啡、喝茶,避免降低药效。</span></p></section></section></section></section></p><p style="letter-spacing: 1px;line-height: 2em;text-align: center;"><span style="font-size: 16px;color: #ff4c41;">(2)输血治疗</span></p><p><section data-support="96编辑器" data-style-id="28090"><section style="margin-top: 10px;margin-bottom: 10px;text-align: center;"><section style="border-width: 1px;border-style: solid;border-color: rgb(255, 19, 13);box-sizing: border-box;"><section style="padding: 10px;color: rgb(255, 19, 13);box-sizing: border-box;"><p style="letter-spacing: 1px;"><br/></p></section></section></section></section><section data-support="96编辑器" data-style-id="31585" style="outline: 0px;font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;"><section style="margin-top: 10px;margin-bottom: 10px;outline: 0px;"><section style="margin-left: auto;outline: 0px;width: 2em;"><br data-filtered="filtered" style="outline: 0px;"/></section><section style="margin-top: -30px;margin-right: 10px;padding: 14px;outline: 0px;background-color: rgb(251, 235, 235);border-radius: 0px 20px 0px 0px;box-sizing: border-box;"><section style="outline: 0px;line-height: 1.75em;letter-spacing: 2px;font-size: 15px;transform: rotateZ(0deg);-webkit-transform: rotateZ(0deg);-moz-transform: rotateZ(0deg);-ms-transform: rotateZ(0deg);-o-transform: rotateZ(0deg);"><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;">&nbsp; &nbsp; &nbsp;&nbsp;在心衰患者中,输血治疗的研究数据有限,改善心衰患者的贫血状况作用有限。输血治疗本身并不会增加心衰患者的死亡率,但应考虑到输血可能带来的相关并发症,包括加重心衰、发热、输血相关急性肺损伤等,因此,输血不能作为改善心衰患者的贫血的长期治疗手段,仅限于在紧急情况下使用,一般来说血红蛋白&gt;80g/L不主张输血治疗。</span></p></section></section></section></section></p><p style="letter-spacing: 1px;line-height: 2em;text-align: center;"><span style="font-size: 16px;color: #ff4c41;">(3)食物补铁</span></p><p><section data-support="96编辑器" data-style-id="28090"><section style="margin-top: 10px;margin-bottom: 10px;text-align: center;"><section style="border-width: 1px;border-style: solid;border-color: rgb(255, 19, 13);box-sizing: border-box;"><section style="padding: 10px;color: rgb(255, 19, 13);box-sizing: border-box;"><p style="letter-spacing: 1px;"><br/></p></section></section></section></section><section data-support="96编辑器" data-style-id="31585" style="outline: 0px;font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;"><section style="margin-top: 10px;margin-bottom: 10px;outline: 0px;"><section style="margin-left: auto;outline: 0px;width: 2em;"><br data-filtered="filtered" style="outline: 0px;"/></section><section style="margin-top: -30px;margin-right: 10px;padding: 14px;outline: 0px;background-color: rgb(251, 235, 235);border-radius: 0px 20px 0px 0px;box-sizing: border-box;"><section style="outline: 0px;line-height: 1.75em;letter-spacing: 2px;font-size: 15px;transform: rotateZ(0deg);-webkit-transform: rotateZ(0deg);-moz-transform: rotateZ(0deg);-ms-transform: rotateZ(0deg);-o-transform: rotateZ(0deg);"><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;">&nbsp; &nbsp; &nbsp;&nbsp;动物血(如鸭血、鸡血、猪血等血制品)铁的含量较高,而且都是易于被人体利用的血红素铁,为补血佳品。此外,可适当多摄入含铁丰富的食物如菠菜、木耳、紫菜、瘦肉、动物肝脏等。维生素C能促进铁的吸收,可以多吃含维生素C丰富的猕猴桃、西红柿、草莓、桔子、酸枣、西兰花、彩椒等。</span></p></section></section></section></section><section data-support="96编辑器" data-style-id="31585" style="outline: 0px;font-family: -apple-system, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif;letter-spacing: 0.544px;white-space: normal;"><section style="margin-top: 10px;margin-bottom: 10px;outline: 0px;"><section style="margin-left: auto;outline: 0px;width: 2em;"><br data-filtered="filtered" style="outline: 0px;"/></section><section style="margin-top: -30px;margin-right: 10px;padding: 14px;outline: 0px;background-color: rgb(251, 235, 235);border-radius: 0px 20px 0px 0px;box-sizing: border-box;"><section style="outline: 0px;line-height: 1.75em;letter-spacing: 2px;font-size: 15px;transform: rotateZ(0deg);-webkit-transform: rotateZ(0deg);-moz-transform: rotateZ(0deg);-ms-transform: rotateZ(0deg);-o-transform: rotateZ(0deg);"><p style="outline: 0px;letter-spacing: 1px;line-height: 2.5em;"><span style="font-size: 16px;">&nbsp; &nbsp; &nbsp; 贫血在心衰患者中普遍存在,铁缺乏是导致贫血最常见的原因,都与患者的预后和死亡密切相关,心衰患者补铁治疗既能改善症状,同时身体机能、运动持久度与生活品质都能获得改善,可以看出心衰患者补铁治疗不仅仅是“雪中送炭”更是“锦上添花”!</span></p></section></section></section></section><section data-support="96编辑器" data-style-id="28090" style="white-space: normal;"><section style="margin-top: 10px;margin-bottom: 10px;text-align: center;"><section style="border-width: 1px;border-style: solid;border-color: rgb(255, 19, 13);box-sizing: border-box;"><section style="padding: 10px;color: rgb(255, 19, 13);box-sizing: border-box;"><p></p><p><strong style="color: rgb(7, 48, 196); letter-spacing: 2px; background-color: rgba(255, 255, 255, 0); font-family: -apple-system-font, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif;">联系方式</strong></p></section></section></section></section></p><p><section style="white-space: normal;letter-spacing: 0.544px;font-family: -apple-system-font, BlinkMacSystemFont, Helvetica Neue, PingFang SC, Hiragino Sans GB, Microsoft YaHei UI, Microsoft YaHei, Arial, sans-serif;"><section><section style="margin-top: 10px;margin-bottom: 10px;"><section style="padding-left: 11px;display: inline-block;width: 676.994px;vertical-align: top;box-sizing: border-box;"><section><section style="display: inline-block;width: 665.997px;vertical-align: top;background-color: rgba(255, 255, 255, 0);border-style: solid;border-width: 1px;border-radius: 0px;border-color: rgb(7, 48, 196);box-sizing: border-box;"><section style="margin-bottom: 10px;"><section style="padding-right: 20px;padding-left: 20px;letter-spacing: 1.8px;line-height: 1.8;box-sizing: border-box;"><p style="color: rgb(62, 62, 62);"><span style="font-size: 16px;">1、咨询株洲恺德心血管病医院订阅号<strong><span style="color: rgb(7, 48, 196);">在线客服;</span></strong><br/>2、咨询电话:<strong><span style="color: rgb(7, 48, 196);">0731-28263456</span></strong></span></p><p style="color: rgb(62, 62, 62);"><span style="font-size: 16px;">3、住院部地址:株洲恺德心血管病医院<span style="color: rgb(7, 48, 196);"><strong>第二住院大楼4楼(心衰中心)</strong></span></span></p><p><span style="font-size: 16px;"><span style="color: rgb(0, 0, 0);">4、</span><strong style="color: rgb(7, 48, 196);">心衰门诊地址</strong><span style="color: rgb(0, 0, 0);"><strong>:</strong></span><strong style="color: rgb(7, 48, 196);">新华西路门诊部2号诊室</strong><span style="color: rgb(0, 0, 0);">(<span style="color: rgb(62, 62, 62);letter-spacing: 1.8px;">华润万家对面</span>)</span></span></p></section></section></section></section></section></section></section><section><section style="border-top: 1px solid rgb(7, 48, 196);line-height: 0;box-sizing: border-box;"><section style="line-height: 0;width: 0px;"><svg viewbox="0 0 1 1" style="vertical-align:top;"></svg></section></section><section style="margin-top: 3px;border-top: 4px solid rgb(7, 48, 196);line-height: 0;box-sizing: border-box;"><section style="line-height: 0;width: 0px;"><svg viewbox="0 0 1 1" style="vertical-align:top;"></svg></section></section></section><section><p style="text-align: right;"><span style="font-size: 12px;letter-spacing: 0.544px;">文案:任承潜</span><span style="letter-spacing: 0.544px;text-align: justify;"></span></p></section></section></p><p style="white-space: normal;"><br/></p><p><br/></p><link rel="stylesheet" href="//bbs.zhuzhou.com/source/plugin/wcn_editor/public/wcn_editor_fit.css?v134_wlU" id="wcn_editor_css"/>
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